Scaling-up of and evidence-based intervention programme in older people with Diabetes and Frailty in LatinAmericam. DIABFRAIL-LATAM: DR. JOSÉ VIÑA 2018
Datos básicos
- Protocolo:
- 825546
- EUDRACT:
- NCT:
- Centro:
- Año de incio:
- 2019
- Año de finalización:
- 2024
Documentos
- No hay documentos
Participantes
Grupos y Plataformas de I+D+i
Financiadores - Promotores
Resultados del Ensayo Clínico
Adult Neural Stem Cell Migration Is Impaired in a Mouse Model of Alzheimer's Disease.
Esteve, Daniel; (...); Lloret, Ana
Article. 10.1007/s12035-021-02620-6. 2022
Anti-Inflammatory Properties of Diet: Role in Healthy Aging.
Stromsnes, Kristine; (...); Olaso-Gonzalez, Gloria
Article. 10.3390/biomedicines9080922. 2021
Bcl-xL as a Modulator of Senescence and Aging.
Mas-Bargues, Cristina, Borras, Consuelo, Vina, Jose
Article. 10.3390/ijms22041527. 2021
Bcl-xL overexpression in T cells preserves muscle mitochondrial structure and function and prevents frailty in old mice
Article. 10.1126/sciadv.adr1378. 2025
BCL-xL, a Mitochondrial Protein Involved in Successful Aging: From C. elegans to Human Centenarians
Review. 10.3390/ijms21020418. 2020
Centenarians: An excellent example of resilience for successful ageing
Review. 10.1016/j.mad.2019.111199. 2020
Diet and exercise in frailty and sarcopenia. Molecular aspects.
Millan-Domingo F; (...); Gomez-Cabrera MC
Article. 10.1016/j.mam.2024.101322. 2024
Early reductive stress and late onset overexpression of antioxidant enzymes in experimental myocardial infarction
Carretero, A; (...); Vina, J
Article. 10.1080/10715762.2020.1735632. 2020
Estrogen Replacement Therapy Induces Antioxidant and Longevity-Related Genes in Women after Medically Induced Menopause.
Article. 10.1155/2021/8101615. 2021
Extracellular vesicles and redox modulation in aging.
Borras, Consuelo; (...); Vina, Jose
Review. 10.1016/j.freeradbiomed.2019.11.032. 2020
FGFR4 regulates tumor subtype differentiation in luminal breast cancer and metastatic disease.
Garcia-Recio, Susana; (...); Perou, Charles M
Article. 10.1172/JCI130323. 2020
Functional Transcriptomic Analysis of Centenarians' Offspring Reveals a Specific Genetic Footprint That May Explain That They Are Less Frail Than Age-Matched Noncentenarians' Offspring.
Ingles, Marta; (...); Vina, Jose
Article. 10.1093/gerona/glac119. 2022
Genistein effect on cognition in prodromal Alzheimer's disease patients. The GENIAL clinical trial.
Article. 10.1186/s13195-022-01097-2. 2022
Genistein, A Phytoestrogen, Delays the Transition to Dementia in Prodromal Alzheimer's Disease Patients.
Viña J, Borrás C, Mas-Bargues C
Article. 10.3233/JAD-240308. 2024
Glucosamine Supplementation Improves Physical Performance in Trained Mice.
De la Rosa, Adrian; (...); Vina, Jose
Article. 10.1249/MSS.0000000000002821. 2022
Glucose 6 phosphate dehydrogenase overexpression rescues the loss of cognition in the double transgenic APP/PS1 mouse model of Alzheimer's disease.
Correas, AG; (...); Viña, J
Article. 10.1016/j.redox.2024.103242. 2024
Glucose 6-P dehydrogenase delays the onset of frailty by protecting against muscle damage.
Arc-Chagnaud, Coralie; (...); Carmen Gomez-Cabrera, Mari
Article. 10.1002/jcsm.12792. 2021
Glucose 6-P Dehydrogenase-An Antioxidant Enzyme with Regulatory Functions in Skeletal Muscle during Exercise.
Garcia-Dominguez, E; (...); Gomez-Cabrera, MC
Article. 10.3390/cells11193041. 2022
Lifelong soya consumption in males does not increase lifespan but increases health span under a metabolic stress such as type 2 diabetes mellitus.
Article. 10.1016/j.mad.2021.111596. 2021
Lipid peroxidation as measured by chromatographic determination of malondialdehyde. Human plasma reference values in health and disease.
Mas-Bargues, Cristina; (...); Vina, Jose
Article. 10.1016/j.abb.2021.108941. 2021
Moderate Red Wine Consumption Increases the Expression of Longevity-Associated Genes in Controlled Human Populations and Extends Lifespan in Drosophila melanogaster.
Gambini, J; (...); Vina, J
Article. 10.3390/antiox10020301. 2021
Modulating Oxidant Levels to Promote Healthy Aging
Vina, J; (...); Gomez-Cabrera, MC
Article. 10.1089/ars.2020.8036. 2020
Molecular mechanisms of cancer cachexia. Role of exercise training.
Tamayo-Torres, E; (...); Gómez-Cabrera, MC
Article. 10.1016/j.mam.2024.101293. 2024
Muscle repair after physiological damage relies on nuclear migration for cellular reconstruction.
Roman, William; (...); Munoz-Canoves, Pura
Article. 10.1126/science.abe5620. 2021
Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models
Costa-Machado, Luis Filipe; (...); Fernandez-Marcos, Pablo J
Article. 10.1038/s41467-023-38410-y. 2023
Pharmacological Properties of Polyphenols: Bioavailability, Mechanisms of Action, and Biological Effects in In Vitro Studies, Animal Models, and Humans.
Stromsnes, Kristine; (...); Gambini, Juan
Article. 10.3390/biomedicines9081074. 2021
Phenotypic upregulation of hexocylceramides and ether-linked phosphocholines as markers of human extreme longevity
Article. 10.1111/acel.14429. 2025
Redox modulation of muscle mass and function.
Gomez-Cabrera, M C; (...); Vina, J
Article. 10.1016/j.redox.2020.101531. 2020
Redox-related biomarkers in physical exercise.
Gomez-Cabrera, MC; (...); Vina, J
Article. 10.1016/j.redox.2021.101956. 2021
Relation Between Genetic Factors and Frailty in Older Adults.
Ingles, Marta; (...); Vina, Jose
Article. 10.1016/j.jamda.2019.03.011. 2019
Residual effects of 12 weeks of power-oriented resistance training plus high-intensity interval training on muscle dysfunction, systemic oxidative damage, and antioxidant capacity after 10 months of training cessation in older people with COPD
Baltasar-Fernandez, Ivan; (...); Alcazar, Julian
Article. 10.1111/sms.14428. 2023
Resveratrol shifts energy metabolism to increase lipid oxidation in healthy old mice
Gimeno-Mallench, L; (...); Vina, J
Article. 10.1016/j.biopha.2019.109130. 2019
Serum Levels of Clusterin, PKR, and RAGE Correlate with Amyloid Burden in Alzheimer's Disease.
Monllor, Paloma; (...); Vina, Jose
Article. 10.3233/JAD-201443. 2021
Small extracellular vesicles from young adipose-derived stem cells prevent frailty, improve health span, and decrease epigenetic age in old mice.
Sanz-Ros, Jorge; (...); Borras, Consuelo
Article. 10.1126/sciadv.abq2226. 2022
The multimodal action of genistein in Alzheimer's and other age-related diseases.
Mas-Bargues, Cristina, Borras, Consuelo, Vina, Jose
Article. 10.1016/j.freeradbiomed.2022.03.021. 2022
The radiographic assessment of lung edema score of lung edema severity correlates with inflammatory parameters in patients with coronavirus disease 2019-Potential new admission biomarkers to predict coronavirus disease 2019 worsening.
Marques P; (...); Sanz MJ
Article. 10.3389/fmed.2022.871714. 2022
Unlocking the biochemical secrets of longevity: balancing healthspan and lifespan.
Article. 10.1002/1873-3468.14963. 2024