Portal de investigación
A multidisciplinary project to advance in basic mechanisms, diagnosis, prediction, and prevention of cardiac damage in reperfused acute myocardial infarction.
Datos básicos
- Protocolo:
- PIE15/00013
- EUDRACT:
- NCT:
- Centro:
- Año de incio:
- 2016
- Año de finalización:
- 2019
Documentos
- No hay documentos
Participantes
Grupos y Plataformas de I+D+i
Financiadores - Promotores
Resultados del Ensayo Clínico
A Novel Micronutrient Blend Mimics Calorie Restriction Transcriptomics in Multiple Tissues of Mice and Increases Lifespan and Mobility in C. elegans
Article. 10.3390/nu12020486. 2020
A randomized controlled trial on carbohydrate antigen 125-guided diuretic treatment versus usual care in patients with acute heart failure and renal dysfunction.
Nunez, Julio; (...); IMPROVE-HF Investigators
Article. 10.1016/j.amjmed.2019.07.041. 2020
An updated overview of e-cigarette impact on human health.
Marques, P, Piqueras, L, Sanz, MJ
Article. 10.1186/s12931-021-01737-5. 2021
Anatomy, immunohistochemistry, and numerical distribution of human splenic microvessels.
Almenar, S; (...); Ruiz-Sauri, A
Article. 10.1016/j.aanat.2019.05.004. 2019
Antigen carbohydrate 125 as a biomarker in heart failure: a narrative review.
Nunez, J; (...); Bayes-Genis, A
Article. 10.1002/ejhf.2295. 2021
BCL-xL, a Mitochondrial Protein Involved in Successful Aging: From C. elegans to Human Centenarians
Review. 10.3390/ijms21020418. 2020
CA125 outperforms NT-proBNP in acute heart failure with severe tricuspid regurgitation
Soler, M; (...); Núñez, J
Article. 10.1016/j.ijcard.2020.03.027. 2020
CA125 outperforms NT-proBNP in acute heart failure with severe tricuspid regurgitation.
Soler, Meritxell; (...); Nunez, Julio
Article. 10.1016/j.ijcard.2020.03.027. 2020
Centenarians overexpress pluripotency-related genes.
Article. 10.1093/gerona/gly168. 2019
Centenarians: An excellent example of resilience for successful ageing
Review. 10.1016/j.mad.2019.111199. 2020
Changes in the spatial distribution of the Purkinje network after acute myocardial infarction in the pig
Garcia-Bustos, V; (...); Ruiz-Sauri, A
Article. 10.1371/journal.pone.0212096. 2019
Development and Long-Term Follow-Up of an Experimental Model of Myocardial Infarction in Rabbits.
Genoves, Patricia; (...); Chorro, Francisco J
Article. 10.3390/ani10091576. 2020
Differential prognostic impact of type 2 diabetes mellitus in women and men with heart failure with preserved ejection fraction.
Palau, Patricia; (...); Nunez, Julio
Article. 10.1016/j.rec.2019.09.002. 2020
Early reductive stress and late onset overexpression of antioxidant enzymes in experimental myocardial infarction
Carretero, A; (...); Vina, J
Article. 10.1080/10715762.2020.1735632. 2020
Early Spot Urinary Sodium and Diuretic Efficiency in Acute Heart Failure and Concomitant Renal Dysfunction.
Minana, Gema; (...); Nunez, Julio
Article. 10.1159/000508178. 2020
Early urinary sodium trajectory and risk of adverse outcomes in acute heart failure and renal dysfunction.
De la Espriella R; (...); Núñez J
Article. 10.1016/j.rec.2020.06.004. 2021
Effect of insulin on readmission for heart failure following a hospitalization for acute heart failure.
Bertomeu-Gonzalez, Vicente; (...); Nunez, Julio
Article. 10.1002/ehf2.12944. 2020
Exercise ECG Testing and Stress Cardiac Magnetic Resonance for Risk Prediction in Patients With Chronic Coronary Syndrome.
Marcos-Garces, Victor; (...); Bodi, Vicente
Article. 10.1097/HCR.0000000000000621. 2022
Extracellular vesicles and redox modulation in aging.
Borras, Consuelo; (...); Vina, Jose
Review. 10.1016/j.freeradbiomed.2019.11.032. 2020
Extracellular Vesicles from Healthy Cells Improves Cell Function and Stemness in Premature Senescent Stem Cells by miR-302b and HIF-1alpha Activation.
Mas-Bargues, Cristina; (...); Borras, Consuelo
Article. 10.3390/biom10060957. 2020
Factors associated with plasma antigen carbohydrate 125 and amino-terminal pro-B-type natriuretic peptide concentrations in acute heart failure
Article. 10.1177/2048872620908033. 2020
Frailty and hospitalization burden in patients with chronic heart failure
Mollar, AA; (...); Nunez, J
Meeting Abstract. 2022
Frailty and Hospitalization Burden in Patients With Chronic Heart Failure.
Mollar A; (...); Núñez J
Article. 10.1016/j.amjcard.2022.08.013. 2022
Functional tricuspid regurgitation and recurrent admissions in patients with acute heart failure
De la Espriella R; (...); Núñez J
Article. 10.1016/j.ijcard.2019.03.051. 2019
Histological and morphometric study of the components of the sinus and atrioventricular nodes in horses and dogs.
Gomez-Torres, F A, Ballesteros-Acuna, L E, Ruiz-Sauri, A
Article. 10.1016/j.rvsc.2019.08.001. 2019
Homocysteine and long-term recurrent infarction following an acute coronary syndrome.
Minana, Gema; (...); Nunez, Julio
Article. 10.5603/CJ.a2020.0170. 2021
Hospitalization following an emergency-department visit for worsening heart failure: The role of left ventricular ejection fraction
Article. 10.1016/j.medcli.2021.09.026. 2022
Hydrogen- and Methane-Based Breath Testing and Outcomes in Patients With Heart Failure
Mollar A; (...); NÚÑez J
Article. 10.1016/j.cardfail.2018.10.004. 2019
Identification to cardiac conduction cells in humans and pigs according to their zonal distribution, using histological, immunohistochemical and morphometric study.
Gomez-Torres, Fabian, Estupinan, H Yesid, Ruiz-Sauri, Amparo
Article. 10.1016/j.rvsc.2021.06.008. 2021
Increased basal antioxidant levels in RCAN1 - deficient mice lowers oxidative injury after acute paraquat insult.
Lloret, Ana; (...); Vina, Jose
Article. 10.1080/10715762.2020.1798002. 2020
Inspiratory Muscle Training and Functional Electrical Stimulation for Treatment of Heart Failure With Preserved Ejection Fraction: The TRAINING-HF Trial.
Palau P; (...); Núñez J
Article. 10.1016/j.rec.2018.01.010. 2019
Interstitial changes after reperfused myocardial infarction in swine: morphometric and genetic analysis.
Rios-Navarro, Cesar; (...); Ruiz-Sauri, Amparo
Article. 10.1186/s12917-020-02465-6. 2020
Lipoprotein(a) and long-term recurrent infarction after an episode of ST-segment elevation acute myocardial infarction.
Minana, Gema; (...); Nunez, Julio
Article. 10.1097/MCA.0000000000000852. 2020
Longitudinal strain in remote non-infarcted myocardium by tissue tracking CMR: characterization, dynamics, structural and prognostic implications.
Gavara, Jose; (...); Bodi, Vicente
Article. 10.1007/s10554-020-01890-w. 2021
Long-term exercise training improves memory in middle-aged men and modulates peripheral levels of BDNF and Cathepsin B
De la Rosa, A; (...); Gomez-Cabrera, MC
Article. 10.1038/s41598-019-40040-8. 2019
Long-Term Prognostic Impact of Estimated Glomerular Filtration Rate on Admission in Patients Hospitalized for Acute Heart Failure.
de la Espriella, Rafael; (...); Nunez, Julio
Article. 10.1159/000526105. 2022
Long-term prognostic implications of revascularization in patients with known or suspected chronic coronary syndromes without ischemia in vasodilator stress cardiovascular magnetic resonance.
Minana, Gema; (...); Bodi, Vicent
Article. 10.1016/j.ijcard.2021.04.037. 2021
Machine Learning Model in Obesity to Predict Weight Loss One Year after Bariatric Surgery: A Pilot Study.
Nadal, E; (...); Real, JT
Article. 10.3390/biomedicines12061175. 2024
Magnetic resonance microscopy and correlative histopathology of the infarcted heart
Perez-Terol, I; (...); Monleon, D
Article. 10.1038/s41598-019-56436-5. 2019
Microvascular Obstruction in ST-Segment Elevation Myocardial Infarction: Looking Back to Move Forward. Focus on CMR.
Rios-Navarro, Cesar; (...); Bodi, Vicente
Review. 10.3390/jcm8111805. 2019
Morphological variations of the conduction system in the atrioventricular zone and its clinical relationship in different species.
Gomez-Torres, Fabian, Ballesteros-Acuna, Luis, Ruiz-Sauri, Amparo
Article. 10.1007/s12565-020-00575-7. 2021
Morphometric analysis of cardiac conduction fibers in horses and dogs, a comparative histological and immunohistochemical study with findings in human hearts.
Gomez-Torres, FA, Estupinan, HY, Ruiz-Sauri, A
Article. 10.1016/j.rvsc.2021.02.013. 2021
Morphometry and comparative histology of sinus and atrioventricular nodes in humans and pigs and their relevance in the prevention of nodal arrhythmias
Gomez-Torres, FA, Sebastian, R, Ruiz-Sauri, A
Article. 10.1016/j.rvsc.2019.12.008. 2020
Novel Immune Features of the Systemic Inflammation Associated with Primary Hypercholesterolemia: Changes in Cytokine/Chemokine Profile, Increased Platelet and Leukocyte Activation
Collado, A; (...); Sanz, MJ
Article. 10.3390/jcm8010018. 2019
Physical exercise in the prevention and treatment of Alzheimer's disease.
De la Rosa, Adrian; (...); Gomez-Cabrera, Mari Carmen
Article. 10.1016/j.jshs.2020.01.004. 2020
Polycerasoidol, a Natural Prenylated Benzopyran with a Dual PPAR alpha/PPAR gamma Agonist Activity and Anti-inflammatory Effect
Bermejo, A; (...); Cortes, D
Article. 10.1021/acs.jnatprod.9b00003. 2019
Prognostic Value of Initial LeftVentricular Remodeling in PatientsWith Reperfused STEMI.
Rodriguez-Palomares, Jose F; (...); Garcia-Dorado, David
Article. 10.1016/j.jcmg.2019.02.025. 2019
Protective Effects of Polyphenols Present in Mediterranean Diet on Endothelial Dysfunction
Stromsnes, K; (...); Gimeno-Mallench, L
Review. 10.1155/2020/2097096. 2020
Redox lipidomics to better understand brain aging and function.
Pamplona R; (...); Viña J
Review. 10.1016/j.freeradbiomed.2019.03.016. 2019
Relation Between Genetic Factors and Frailty in Older Adults.
Ingles, Marta; (...); Vina, Jose
Article. 10.1016/j.jamda.2019.03.011. 2019
Relation of Low Lymphocyte Count to Frailty and its 11) Usefulness as a Prognostic Biomarker in Patients >65 Years of Age With Acute Coronary Syndrome
Nunez, J; (...); Sanchis, J
Article. 10.1016/j.amjcard.2020.01.006. 2020
Relationship between Diet, Microbiota, and Healthy Aging.
Sanchez-Morate, Elisa; (...); Mas-Bargues, Cristina
Article. 10.3390/biomedicines8080287. 2020
Relevance of Oxygen Concentration in Stem Cell Culture for Regenerative Medicine
Mas-Bargues, C; (...); Borras, C
Review. 10.3390/ijms20051195. 2019
Resveratrol shifts energy metabolism to increase lipid oxidation in healthy old mice
Gimeno-Mallench, L; (...); Vina, J
Article. 10.1016/j.biopha.2019.109130. 2019
Right ventricular function and iron deficiency in acute heart failure.
Minana, Gema; (...); Nunez, Julio
Article. 10.1093/ehjacc/zuaa028. 2021
Role of antiangiogenic VEGF-A165b in angiogenesis and systolic function after reperfused myocardial infarction.
Rios-Navarro, Cesar; (...); Bodi, Vicente
Article. 10.1016/j.rec.2020.03.013. 2021
Role of PCSK9 in the course of ejection fraction change after ST-segment elevation myocardial infarction: a pilot study
Article. 10.1002/ehf2.12533. 2020
Sarcopenia, frailty and their prevention by exercise.
Nascimento CM; (...); Viña J
Review. 10.1016/j.freeradbiomed.2018.08.035. 2019
Sex Differences in Age-Associated Type 2 Diabetes in Rats-Role of Estrogens and Oxidative Stress
Diaz, A; (...); Borras, C
Article. 10.1155/2019/6734836. 2019
SGLT-2 (Sodium-Glucose Cotransporter 2) Inhibition Reduces Ang II (Anciotensin II)-Induced Dissecting Abdominal Aortic Aneurysm in ApoE (Apolipoprotein E) Knockout Mice
Ortega, R; (...); Piqueras, L
Article. 10.1161/ATVBAHA.119.312659. 2019
Soluble ST2 and Diuretic Efficiency in Acute Heart Failure and Concomitant Renal Dysfunction.
Espriella, Rafael de la; (...); Nunez, Julio
Article. 10.1016/j.cardfail.2020.10.002. 2021
Strain by Feature Tracking: A Short Summary of the Journey of CMR in STEMI.
Editorial Material. 10.1016/j.jcmg.2018.08.009. 2019
Systemic Inflammation in Metabolic Syndrome: Increased Platelet and Leukocyte Activation, and Key Role of CX3CL1/CX3CR1 and CCL2/CCR2 Axes in Arterial Platelet-Proinflammatory Monocyte Adhesion.
Marques, Patrice; (...); Sanz, Maria-Jesus
Article. 10.3390/jcm8050708. 2019
The free radical theory of frailty: Mechanisms and opportunities for interventions to promote successful aging.
Article. 10.1016/j.freeradbiomed.2019.01.045. 2019
The influence of sex and body mass index on the association between soluble neprilysin and risk of heart failure hospitalizations.
Nunez, Julio; (...); Bayes-Genis, Antoni
Article. 10.1038/s41598-021-85490-1. 2021
The Relationship between Diet and Frailty in Aging.
Gimeno-Mallench, Lucia; (...); Gambini, Juan
Article. 10.2174/1871530320666200513083212. 2020
Transcriptomic profile of epileptic children treated with ketogenic therapies.
Ruiz-Herrero, Jana; (...); Vina, Jose
Article. 10.31083/j.jin2101031. 2022
Two-Week Aflibercept or Erlotinib Administration Does Not Induce Changes in Intestinal Morphology in Male Sprague-Dawley Rats But Aflibercept Affects Serum and Urine Metabolic Profiles
Forsgard, RA; (...); Osterlund, P
Article. 10.1016/j.tranon.2019.04.019. 2019
Vasodilator Stress CMR and All-Cause Mortality in Stable Ischemic Heart Disease: A Large Retrospective Registry.
Marcos-Garces V; (...); Bodi V
Article. 10.1016/j.jcmg.2020.02.027. 2020
