Caracterización de las alteraciones neurológicas y cerebrales en pacientes con encefalopatía hepática mínima. Contribucu¡ión de la Inflamación. Implicaciones diagnósticas y terapéuticas
Datos básicos
- Protocolo:
- PI18/00150
- EUDRACT:
- NCT:
- Centro:
- Año de incio:
- 2019
- Año de finalización:
- 2021
Documentos
- No hay documentos
Grupos y Plataformas de I+D+i
Financiadores - Promotores
Resultados del Ensayo Clínico
A Look into Liver Mitochondrial Dysfunction as a Hallmark in Progression of Brain Energy Crisis and Development of Neurologic Symptoms in Hepatic Encephalopathy.
Kosenko, Elena; (...); Montoliu, Carmina
Article. 10.3390/jcm9072259. 2020
Extracellular Vesicles from Hyperammonemic Rats Induce Neuroinflammation and Motor Incoordination in Control Rats.
Izquierdo-Altarejos, Paula; (...); Felipo, Vicente
Article. 10.3390/cells9030572. 2020
Is NMDA-Receptor-Mediated Oxidative Stress in Mitochondria of Peripheral Tissues the Essential Factor in the Pathogenesis of Hepatic Encephalopathy?
Kosenko, Elena; (...); Montoliu, Carmina
Article. 10.3390/jcm11030827. 2022
Letter to the Editor - Reply to 'Ammonia - an old friend with a new area of application.
Tranah, Thomas H; (...); Shawcross, Debbie L
Letter. 10.1016/j.jhep.2022.09.023. 2023
Metabolic syndrome is associated with poor response to rifaximin in minimal hepatic encephalopathy.
Ballester, Maria-Pilar; (...); Montoliu, Carmina
Article. 10.1038/s41598-022-06416-z. 2022
Minimal hepatic encephalopathy is associated to alterations in eye movements.
Casanova-Ferrer, F; (...); Montoliu, C
Article. 10.1038/s41598-022-21230-3. 2022
Motor and Cognitive Performance in Patients with Liver Cirrhosis with Minimal Hepatic Encephalopathy.
San Martin-Valenzuela, Constanza; (...); Montoliu, Carmina
Article. 10.3390/jcm9072154. 2020
Multi-omic analysis unveils biological pathways in peripheral immune system associated to minimal hepatic encephalopathy appearance in cirrhotic patients.
Rubio, Teresa; (...); Montoliu, Carmina
Article. 10.1038/s41598-020-80941-7. 2021
Patients with Minimal Hepatic Encephalopathy Show Altered Thermal Sensitivity and Autonomic Function.
Rega, Dalia; (...); Montoliu, Carmina
Article. 10.3390/jcm10020239. 2021
Plasma ammonia levels predict hospitalisation with liver-related complications and mortality in clinically stable outpatients with cirrhosis.
Tranah, Thomas H; (...); Shawcross, Debbie L
Article. 10.1016/j.jhep.2022.07.014. 2022
Plasma Extracellular Vesicles Play a Role in Immune System Modulation in Minimal Hepatic Encephalopathy.
Gallego, JJ; (...); Montoliu, C
Article. 10.3390/ijms232012335. 2022
Selective improvement by rifaximin of changes in the immunophenotype in patients who improve minimal hepatic encephalopathy
Mangas-Losada, A; (...); Felipo, V
Article. 10.1186/s12967-019-2046-5. 2019
Synthesis of benzopyran derivatives as PPAR alpha and/or PPAR gamma activators
Bermejo, A; (...); Cabedo, N
Article. 10.1016/j.bmc.2019.115162. 2019
Tadalafil Treatment Improves Inflammation, Cognitive Function, And Mismatch Negativity Of Patients With Low Urinary Tract Symptoms And Erectile Dysfunction
Urios, A; (...); Montoliu, C
Article. 10.1038/s41598-019-53136-y. 2019
The Erythrocytic Hypothesis of Brain Energy Crisis in Sporadic Alzheimer Disease: Possible Consequences and Supporting Evidence
Kosenko, E; (...); Montoliu, C
Review. 10.3390/jcm9010206. 2020