Caracterización de las alteraciones neurológicas y cerebrales en pacientes con encefalopatía hepática mínima. Contribucu¡ión de la Inflamación. Implicaciones diagnósticas y terapéuticas

Datos básicos

Protocolo:
PI18/00150
EUDRACT:
NCT:
Centro:
Año de incio:
2019
Año de finalización:
2021
PROYECTO DE INVESTIGACIÓN NACIONAL F.COMPETITIVA FIN. PUBLICA 171.820,00 €

Documentos

  • No hay documentos

Participantes

Grupos y Plataformas de I+D+i

Financiadores - Promotores

INSTITUTO SALUD CARLOS III

Resultados del Ensayo Clínico


A Look into Liver Mitochondrial Dysfunction as a Hallmark in Progression of Brain Energy Crisis and Development of Neurologic Symptoms in Hepatic Encephalopathy.

Kosenko, Elena; (...); Montoliu, Carmina

Article. 10.3390/jcm9072259. 2020


Extracellular Vesicles from Hyperammonemic Rats Induce Neuroinflammation and Motor Incoordination in Control Rats.

Izquierdo-Altarejos, Paula; (...); Felipo, Vicente

Article. 10.3390/cells9030572. 2020


Is NMDA-Receptor-Mediated Oxidative Stress in Mitochondria of Peripheral Tissues the Essential Factor in the Pathogenesis of Hepatic Encephalopathy?

Kosenko, Elena; (...); Montoliu, Carmina

Article. 10.3390/jcm11030827. 2022


Letter to the Editor - Reply to 'Ammonia - an old friend with a new area of application.

Tranah, Thomas H; (...); Shawcross, Debbie L

Letter. 10.1016/j.jhep.2022.09.023. 2023


Metabolic syndrome is associated with poor response to rifaximin in minimal hepatic encephalopathy.

Ballester, Maria-Pilar; (...); Montoliu, Carmina

Article. 10.1038/s41598-022-06416-z. 2022


Minimal hepatic encephalopathy is associated to alterations in eye movements.

Casanova-Ferrer, F; (...); Montoliu, C

Article. 10.1038/s41598-022-21230-3. 2022


Motor and Cognitive Performance in Patients with Liver Cirrhosis with Minimal Hepatic Encephalopathy.

San Martin-Valenzuela, Constanza; (...); Montoliu, Carmina

Article. 10.3390/jcm9072154. 2020


Multi-omic analysis unveils biological pathways in peripheral immune system associated to minimal hepatic encephalopathy appearance in cirrhotic patients.

Rubio, Teresa; (...); Montoliu, Carmina

Article. 10.1038/s41598-020-80941-7. 2021


Patients with Minimal Hepatic Encephalopathy Show Altered Thermal Sensitivity and Autonomic Function.

Rega, Dalia; (...); Montoliu, Carmina

Article. 10.3390/jcm10020239. 2021


Plasma ammonia levels predict hospitalisation with liver-related complications and mortality in clinically stable outpatients with cirrhosis.

Tranah, Thomas H; (...); Shawcross, Debbie L

Article. 10.1016/j.jhep.2022.07.014. 2022


Plasma Extracellular Vesicles Play a Role in Immune System Modulation in Minimal Hepatic Encephalopathy.

Gallego, JJ; (...); Montoliu, C

Article. 10.3390/ijms232012335. 2022


Selective improvement by rifaximin of changes in the immunophenotype in patients who improve minimal hepatic encephalopathy

Mangas-Losada, A; (...); Felipo, V

Article. 10.1186/s12967-019-2046-5. 2019


Synthesis of benzopyran derivatives as PPAR alpha and/or PPAR gamma activators

Bermejo, A; (...); Cabedo, N

Article. 10.1016/j.bmc.2019.115162. 2019


Tadalafil Treatment Improves Inflammation, Cognitive Function, And Mismatch Negativity Of Patients With Low Urinary Tract Symptoms And Erectile Dysfunction

Urios, A; (...); Montoliu, C

Article. 10.1038/s41598-019-53136-y. 2019


The Erythrocytic Hypothesis of Brain Energy Crisis in Sporadic Alzheimer Disease: Possible Consequences and Supporting Evidence

Kosenko, E; (...); Montoliu, C

Review. 10.3390/jcm9010206. 2020


Campos de Estudio

Compartir