Estudio experimental in vivo e in vitro y la aplicación clínica del impacto de las proteínas del complejo Rhabphilin-Rab en el desarrollo del daño renal y cardiovascular.

Datos básicos

PROYECTO DE INVESTIGACIÓN NACIONAL F.COMPETITIVA FIN. PUBLICA 194.205,00 € PI16/01402 Año de incio: 2017 Año de finalización: 2019

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Grupos y Plataformas de I+D+i

Financiadores - Promotores

INSTITUTO SALUD CARLOS III

Resultados del Ensayo Clínico


Acute kidney injury in heart failure: a population study

Holgado, JL; (...); Ruiz, A

Article. 10.1002/ehf2.12595. 2020


Arsenic, cadmium, and selenium exposures and bone mineral density-related endpoints: The HORTEGA study.

Galvez-Fernandez, Marta; (...); Martin-Escudero, Juan Carlos

Article. 10.1016/j.freeradbiomed.2020.10.318. 2021


Cardiac magnetic resonance-derived fibrosis, strain and molecular biomarkers of fibrosis in hypertensive heart disease.

Pichler, Gernot; (...); Maceira, Alicia

Article. 10.1097/HJH.0000000000002504. 2020


Cohort profile: the Hortega Study for the evaluation of non-traditional risk factors of cardiometabolic and other chronic diseases in a general population from Spain.

Tellez-Plaza M; (...); Martin-Escudero JC

Article. 10.1136/bmjopen-2018-024073. 2019


Gene-environment interaction analysis of redox-related metals and genetic variants with plasma metabolic patterns in a general population from Spain: The Hortega Study.

Galvez-Fernandez, M; (...); Monleon, D

Article. 10.1016/j.redox.2022.102314. 2022


Healthy lifestyle, metabolomics and incident type 2 diabetes in a population-based cohort from Spain.

Delgado-Velandia, M; (...); Sotos-Prieto, M

Article. 10.1186/s12966-021-01219-3. 2022


High miR-126-3p levels associated with cardiovascular events in a general population

Martinez-Arroyo, Olga; (...); Cortes, Raquel

Article. 10.1016/j.ejim.2023.04.013. 2023


Immune-unreactive urinary albumin as a predictor of cardiovascular events: the Hortega Study.

Martínez F; (...); Redon J

Article. 10.1093/ndt/gfy087. 2019


Impact of Acute Hemoglobin Falls in Heart Failure Patients: A Population Study.

Lopez, Cristina; (...); Redon, Josep

Article. 10.3390/jcm9061869. 2020


Incidence and impact of atrial fibrillation in heart failure patients: real-world data in a large community.

Diaz, J; (...); Forner, MJ

Article. 10.1002/ehf2.14124. 2022


Optimization of small RNA library preparation protocol from human urinary exosomes

Olivares, D; (...); Cortes, R

Article. 10.1186/s12967-020-02298-9. 2020


Rabphilin involvement in filtration and molecular uptake in Drosophila nephrocytes suggests a similar role in human podocytes.

Selma-Soriano, Estela; (...); Redon, Josep

Article. 10.1242/dmm.041509. 2020


Rabphilin silencing causes dilated cardiomyopathy in a Drosophila model of nephrocyte damage.

Selma-Soriano, E; (...); Redon, J

Article. 10.1038/s41598-021-94710-7. 2021


RAB-RABPHILIN SYSTEM IN INJURED HUMAN PODOCYTES STRESSED BY GLUCOSE OVERLOAD AND ANGIOTENSIN II.

Martinez-Arroyo, Olga; (...); Cortes, Raquel

Article. 10.1152/ajprenal.00077.2020. 2020


Real world data of anticoagulant treatment in non-valvular atrial fibrillation across renal function status.

Calderon, Jose Miguel; (...); Forner, Maria Jose

Article. 10.1038/s41598-022-10164-5. 2022


Small Rab GTPases in Intracellular Vesicle Trafficking: The Case of Rab3A/Raphillin-3A Complex in the Kidney.

Martinez-Arroyo, O; (...); Redon, J

Article. 10.3390/ijms22147679. 2021


Supervised Analysis for Phenotype Identification: The Case of Heart Failure Ejection Fraction Class.

Lopez, Cristina; (...); Redon, Josep

Article. 10.3390/bioengineering8060085. 2021


Therapeutic Potential of Extracellular Vesicles in Hypertension-Associated Kidney Disease.

Martinez-Arroyo, Olga; (...); Cortes, Raquel

Article. 10.1161/HYPERTENSIONAHA.120.16064. 2021


Urinary- and Plasma-Derived Exosomes Reveal a Distinct MicroRNA Signature Associated With Albuminuria in Hypertension.

Perez-Hernandez, Javier; (...); Cortes, Raquel

Article. 10.1161/HYPERTENSIONAHA.120.16598. 2021


Urinary exosomal miR-146a as a marker of albuminuria, activity changes and disease flares in lupus nephritis.

Perez-Hernandez, Javier; (...); Cortes, Raquel

Article. 10.1007/s40620-020-00832-y. 2021


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