The Relationship between Diet and Frailty in Aging.

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Autores de INCLIVA

Participantes ajenos a INCLIVA

  • Sanchez-Morate, Elisa
  • Parejo-Pedrajas, Sergi
  • Stromsnes, Kristine

Grupos y Plataformas de I+D+i

Abstract

The increase in lifespan in the 20th century entails an increase in the elderly population. This brings a new challenge for society, causing people to have physical and mental limitations caused by age-related diseases, such as frailty. Frailty is clinically characterized by multisystem pathophysiological processes, such as chronic inflammation, immune activation, dysregulation of the musculoskeletal and endocrine systems, oxidative stress, energy imbalances, mitochondrial dysfunction, and sarcopenia. Elderly should consume energy in amounts close to those in what is currently accepted as a balanced diet. However, an increase in protein intake may be recommended for elderly people as long as there is no kidney damage. This increase could help fight the loss of muscle mass associated with age. Additionally, vitamin and mineral intakes are often insufficient in their diets. Therefore, diet should be adapted not only to their age, but also to the pathologies associated with aging. Through these measures we can reduce the prevalence of comorbidity and thereby increase health span. Therefore, both physical and nutritional interventions, including functional foods and nutraceuticals, should be taken into account. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Datos de la publicación

ISSN/ISSNe:
2212-3873, 1871-5303

ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS  Bentham Science Publishers

Tipo:
Article
Páginas:
1373-1382
PubMed:
32400339

Citas Recibidas en Web of Science: 17

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Keywords

  • Frailty; aging; diet; energy balance; healthspan; nutrition

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