Portal de investigación
Identificación y validación de nuevas terapias, modelos preclínicos y marcadores de respuesta terapéutica en neuroblastoma. (PI17/01558).
Datos básicos
- Protocolo:
- PI17/01558
- EUDRACT:
- NCT:
- Centro:
- HOSPITAL CLINICO UNIVERSITARIO DE VALENCIA
- Año de incio:
- 2018
- Año de finalización:
- 2020
Documentos
- No hay documentos
Grupos y Plataformas de I+D+i
Financiadores - Promotores
Resultados del Ensayo Clínico
11q Deletion or ALK Activity Curbs DLG2 Expression to Maintain an Undifferentiated State in Neuroblastoma.
Siaw, Joachim Tetteh; (...); Martinsson, Tommy
Article. 10.1016/j.celrep.2020.108171. 2020
A three-dimensional bioprinted model to evaluate the effect of stiffness on neuroblastoma cell cluster dynamics and behavior.
Monferrer, Ezequiel; (...); Noguera, Rosa
Article. 10.1038/s41598-020-62986-w. 2020
Age Dependency of the Prognostic Impact of Tumor Genomics in Localized Resectable MYCN-Nonamplified Neuroblastomas. Report From the SIOPEN Biology Group on the LNESG Trials and a COG Validation Group
Ambros, IM; (...); Ambros, PF
Article. 10.1200/JCO.18.02132. 2020
Characterizing the Invasive Tumor Front of Aggressive Uterine Adenocarcinoma and Leiomyosarcoma.
Sanegre, S; (...); Noguera, R
Article. 10.3389/fcell.2021.670185. 2021
Digital Image Analysis Applied to Tumor Cell Proliferation, Aggressiveness, and Migration-Related Protein Synthesis in Neuroblastoma 3D Models.
Monferrer, Ezequiel; (...); Noguera, Rosa
Article. 10.3390/ijms21228676. 2020
Extra-Adrenal Adult Neuroblastoma With Aberrant Germ Cell Marker Expression: Maturation After Chemotherapy as an Important Clue to a Challenging Diagnosis.
Martinez-Ciarpaglini C; (...); Navarro S
Article. 10.1177/1066896919835945. 2019
Frequency and Prognostic Impact of ALK Amplifications and Mutations in the European Neuroblastoma Study Group (SIOPEN) High-Risk Neuroblastoma Trial (HR-NBL1).
Bellini, Angela; (...); Schleiermacher, Gudrun
Article. 10.1200/JCO.21.00086. 2021
High Oct4 expression: implications in the pathogenesis of neuroblastic tumours.
Monferrer E; (...); Noguera R
Article. 10.1186/s12885-018-5219-3. 2019
Imbalance between genomic gain and loss identifies high-risk neuroblastoma patients with worse outcomes.
Fernandez-Blanco, Beatriz; (...); Noguera, Rosa
Article. 10.1016/j.neo.2020.11.001. 2020
Impact of extracellular matrix stiffness on genomic heterogeneity in MYCN-amplified neuroblastoma cell line.
Lopez-Carrasco, Amparo; (...); Noguera, Rosa
Article. 10.1186/s13046-020-01729-1. 2020
Integrating digital pathology with transcriptomic and epigenomic tools for predicting metastatic uterine tumor aggressiveness.
Sonzini, Giorgia; (...); Noguera, Rosa
Article. 10.3389/fcell.2022.1052098. 2022
Integrating the Tumor Microenvironment into Cancer Therapy.
Sanegre, Sabina; (...); Alvaro Naranjo, Tomas
Article. 10.3390/cancers12061677. 2020
Intra-Tumour Genetic Heterogeneity and Prognosis in High-Risk Neuroblastoma.
Lopez-Carrasco, Amparo; (...); Noguera, Rosa
Article. 10.3390/cancers13205173. 2021
SuperHistopath: A Deep Learning Pipeline for Mapping Tumor Heterogeneity on Low-Resolution Whole-Slide Digital Histopathology Images.
Zormpas-Petridis, K; (...); Yuan, YY
Article. 10.3389/fonc.2020.586292. 2021
The topology of vitronectin: A complementary feature for neuroblastoma risk classification based on computer-aided detection
Vicente-Munuera, P; (...); Escudero, LM
Article. 10.1002/ijc.32495. 2020
The tumour microenvironment as an integrated framework to understand cancer biology
Burgos-Panadero, R; (...); Noguera, R
Review. 10.1016/j.canlet.2019.07.010. 2019
Therapeutic Opportunities in Neuroblastoma Using Nanotechnology
Rodriguez-Nogales, C; (...); Blanco-Prieto, MJ
Review. 10.1124/jpet.118.255067. 2019
Unraveling the extracellular matrix-tumor cell interactions to aid better targeted therapies for neuroblastoma.
Burgos-Panadero, Rebeca; (...); Noguera, Rosa
Article. 10.1016/j.ijpharm.2021.121058. 2021
Vitronectin as a molecular player of the tumor microenvironment in neuroblastoma
Burgos-Panadero, R; (...); Noguera, R
Article. 10.1186/s12885-019-5693-2. 2019
