Portal de investigación
Modulación inmunofarmacológica de la inflamación sistémica asociada a desórdenes metabólicos. Búsqueda de nuevas dianas terapéuticas y síntesis de fármacos novedosos.
Datos básicos
- Protocolo:
- SAF2014-57845-R
- EUDRACT:
- NCT:
- Centro:
- Año de incio:
- 2015
- Año de finalización:
- 2017
Documentos
- No hay documentos
Participantes
Grupos y Plataformas de I+D+i
Financiadores - Promotores
MINISTERIO ECONOMIA Y COMPETITIVIDAD
Resultados del Ensayo Clínico
1-(2 '-Bromobenzyl)-6,7-dihydroxy-N-methyl-tetrahydroisoquinoline and 1,2-Demethyl-nuciferine as Agonists in Human D-2 Dopamine Receptors
Silva, AG; (...); Cabedo, N
Article. 10.1021/acs.jnatprod.9b00921. 2020
Disruption of the CCL1-CCR8 axis inhibits vascular Treg recruitment and function and promotes atherosclerosis in mice.
Vila-Caballer, Marian; (...); Andres, Vicente
Article. 10.1016/j.yjmcc.2019.05.009. 2019
Machine Learning Model in Obesity to Predict Weight Loss One Year after Bariatric Surgery: A Pilot Study.
Nadal, E; (...); Real, JT
Article. 10.3390/biomedicines12061175. 2024
Novel Immune Features of the Systemic Inflammation Associated with Primary Hypercholesterolemia: Changes in Cytokine/Chemokine Profile, Increased Platelet and Leukocyte Activation
Collado, A; (...); Sanz, MJ
Article. 10.3390/jcm8010018. 2019
Peripheral blood levels of CXCL10 are a useful marker for diabetic polyneuropathy in subjects with type 2 diabetes.
Ascaso, Pilar; (...); Real, Jose T
Article. 10.1111/ijcp.14302. 2021
Polycerasoidol, a Natural Prenylated Benzopyran with a Dual PPAR alpha/PPAR gamma Agonist Activity and Anti-inflammatory Effect
Bermejo, A; (...); Cortes, D
Article. 10.1021/acs.jnatprod.9b00003. 2019
Synthesis and biological evaluation of sphingosine kinase 2 inhibitors with anti-inflammatory activity
Vettorazzi, M; (...); Enriz, RD
Article. 10.1002/ardp.201800298. 2019
Synthesis of benzopyran derivatives as PPAR alpha and/or PPAR gamma activators
Bermejo, A; (...); Cabedo, N
Article. 10.1016/j.bmc.2019.115162. 2019
Systemic Inflammation in Metabolic Syndrome: Increased Platelet and Leukocyte Activation, and Key Role of CX3CL1/CX3CR1 and CCL2/CCR2 Axes in Arterial Platelet-Proinflammatory Monocyte Adhesion.
Marques, Patrice; (...); Sanz, Maria-Jesus
Article. 10.3390/jcm8050708. 2019
