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Functional tricuspid regurgitation and recurrent admissions in patients with acute heart failure

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Autores de INCLIVA

Participantes ajenos a INCLIVA

  • Soler M
  • Núñez E
  • Lupón J

Grupos y Plataformas de I+D+i

Abstract

Background: Functional tricuspid regurgitation (TR) is a common echocardiographic finding in patients with heart failure (HF), and its role in disease progression and prognosis stratification is becoming increasingly relevant in recent years. However, data regarding its association with the burden of HF-readmission is scarce. In this work, we sought to evaluate the association between TR severity and HF-related readmissions following a hospitalization for acute heart failure (AHF). Methods: We prospectively included a cohort of 2101 patients admitted with the diagnosis of AHF. TR severity was assessed using a multiparametric integrative approach, and classified as none, mild, moderate, and severe. We used negative binomial regression to identify the association between TR grade and HF-related recurrent admissions. The risk associated to severity of TR was expressed as incidence rate ratio (IRR). Results: At a median follow-up of 2.53 years (IQR: 1.03-4.36), 978 (46.5%) patients died, and 1657 HF-readmissions occurred in 842 patients (40.0%). The proportion of patients with two or more admissions was 18.4%. The proportion of patients with moderate to severe TR was 17.2%. There was a step wise increase in the incidence of readmissions from none to severe TR. After multivariable adjustment, only patients with severe TR were independently associated with higher risk of recurrent HF admissions (IRR = 1.34, CI 95%: 1.05-1.71; p = .019). Conclusions: In patients with AHF, severe functional TR is independently associated with an increased risk of long-term recurrent HF hospitalizations. (C) 2019 Elsevier B.V. All rights reserved.

© 2019 Elsevier B.V. All rights reserved

Datos de la publicación

ISSN/ISSNe:
0167-5273, 1874-1754

INTERNATIONAL JOURNAL OF CARDIOLOGY  ELSEVIER IRELAND LTD

Tipo:
Article
Páginas:
83-88
PubMed:
30955879

Citas Recibidas en Web of Science: 21

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Keywords

  • Functional tricuspid regurgitation; Acute hear failure; Recurrent heart failure admissions

Campos de Estudio

Financiación

INSTITUTO SALUD CARLOS III (CB16/11/00420)
INSTITUTO SALUD CARLOS III (PIE15/00013)

Proyectos y Estudios Clínicos

A multidisciplinary project to advance in basic mechanisms, diagnosis, prediction, and prevention of cardiac damage in reperfused acute myocardial infarction.

Investigador Principal: VICENT BODÍ PERIS

PIE15/00013 . INSTITUTO SALUD CARLOS III . 2016

INCORPORACIÓN DE NUEVAS ÁREAS TEMÁTICAS Y NUEVOS GRUPOS AL CONSORCIO CIBER

Investigador Principal: JUAN SANCHIS FORES

CB16/11/00420 . INSTITUTO SALUD CARLOS III

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