Medicina personalizada en pacientes con cáncer colorrectal localizado: abordaje multiómico de la Enfermedad Mínima Residual en biopsia líquida y modelos de organoides

Datos básicos

Protocolo:
PI18/01909
EUDRACT:
NCT:
Centro:
HOSPITAL CLINICO UNIVERSITARIO DE VALENCIA
Año de incio:
2019
Año de finalización:
2021
PROYECTO DE INVESTIGACIÓN NACIONAL F.COMPETITIVA FIN. PUBLICA 141.570,00 €

Documentos

  • No hay documentos

Participantes

Grupos y Plataformas de I+D+i

Financiadores - Promotores

INSTITUTO SALUD CARLOS III

Resultados del Ensayo Clínico


"Proteotranscriptomic analysis of advanced colorectal cancer patient derived organoids for drug sensitivity prediction"

Papaccio, Federica; (...); Castillo, Josefa

Article. 10.1186/s13046-022-02591-z. 2023


Addition of nivolumab to chemotherapy in patients with advanced gastric cancer: a relevant step ahead, but still many questions to answer.

Smyth, Elizabeth C, Cervantes, Andres

Editorial Material. 10.1136/esmoopen-2020-001107. 2020


BISPECIFIC ANTIBODIES INCREASE THE THERAPEUTIC WINDOW OF CD40 AGONISTS THROUGH SELECTIVE DENDRITIC CELL TARGETING

Ciardiello, D; (...); Cervantes, A

News Item. 2022


Circulating Tumor DNA Detection by Digital-Droplet PCR in Pancreatic Ductal Adenocarcinoma: A Systematic Review.

Huerta, Marisol; (...); Ibarrola-Villava, Maider

Article. 10.3390/cancers13050994. 2021


Circulating Tumor DNA in Stage III Colorectal Cancer, beyond Minimal Residual Disease Detection, toward Assessment of Adjuvant Therapy Efficacy and Clinical Behavior of Recurrences.

Henriksen, Tenna Vesterman; (...); Andersen, Claus Lindbjerg

Article. 10.1158/1078-0432.CCR-21-2404. 2022


Clinical management of metastatic colorectal cancer in the era of precision medicine.

Ciardiello, F; (...); Cervantes, A

Article. 10.3322/caac.21728. 2022


Epigenetic Mechanisms Are Involved in the Oncogenic Properties of ZNF518B in Colorectal Cancer.

Gimeno-Valiente, F; (...); Castillo, J

Article. 10.3390/cancers13061433. 2021


Improving tumor budding evaluation in colon cancer by extending the assessment area in colectomy specimen.

Martinez-Ciarpaglini, Carolina; (...); Cervantes, Andres

Article. 10.1111/his.13900. 2019


In the literature: April 2020

Gambardella, V; (...); Cervantes, A

Editorial Material. 10.1136/esmoopen-2020-000749. 2020


In the literature: April 2021.

Martin-Martorell, P; (...); Cervantes, A

News Item. 10.1016/j.esmoop.2021.100116. 2021


In the literature: April 2022.

Ciardiello, D; (...); Cervantes, A

Editorial Material. 10.1016/j.esmoop.2022.100479. 2022


In the literature: August 2020.

Gambardella, Valentina; (...); Cervantes, Andres

Article. 10.1136/esmoopen-2020-000909. 2020


In the literature: December 2019

Gambardella, V; (...); Cervantes, A

Editorial Material. 10.1136/esmoopen-2019-000642. 2020


In the literature: December 2020.

Gambardella, V; (...); Cervantes, A

News Item. 10.1016/j.esmoop.2020.100009. 2021


In the literature: December 2021.

Montagut C; (...); Cervantes A

News Item. 10.1016/j.esmoop.2021.100352. 2022


In the literature: February 2020

Roda, D; (...); Cervantes, A

Editorial Material. 10.1136/esmoopen-2020-000680. 2020


In the literature: February 2021

Cejalvo, JM; (...); Cervantes, A

News Item. 10.1016/j.esmoop.2021.100061. 2021

  • Open Access.

In the literature: February 2022.

Gambardella, V; (...); Cervantes, A

Editorial Material. 10.1016/j.esmoop.2022.100411. 2022


In the literature: June 2020.

Roda, Desamparados; (...); Cervantes, Andres

Article. 10.1136/esmoopen-2020-000832. 2020


In the literature: June 2021.

Gambardella, V; (...); Cervantes, A

News Item. 10.1016/j.esmoop.2021.100186. 2021


In the literature: October 2019

Editorial Material. 10.1136/esmoopen-2019-000613. 2019

  • Open Access.

In the literature: October 2020.

Gambardella, Valentina; (...); Cervantes, Andres

Article. 10.1136/esmoopen-2020-001048. 2020


In the literature: October 2021.

Gambardella, V; (...); Cervantes, A

News Item. 10.1016/j.esmoop.2021.100285. 2021


Integrative immune transcriptomic classification could improve patient selection for precision immunotherapy in advanced gastroesophageal adenocarcinoma

Segura, MC; (...); Fleitas, TC

Meeting Abstract. 10.1016/j.annonc.2022.09.065. 2022

  • Open Access.

Molecular profiling of advanced solid tumours. The impact of experimental molecular-matched therapies on cancer patient outcomes in early-phase trials: the MAST study.

Gambardella, Valentina; (...); Roda, Desamparados

Article. 10.1038/s41416-021-01502-x. 2021


MULTIOMIC PROFILING OF CHECKPOINT INHIBITOR-TREATED MELANOMA: IDENTIFYING PREDICTORS OF RESPONSE AND RESISTANCE AS WELL AS MARKERS OF BIOLOGICAL DISCORDANCE

Gambardella, V; (...); Cervantes, A

News Item. 2022


Neoadjuvant Chemotherapy in Locally Advanced Rectal Cancer.

Papaccio, Federica; (...); Cervantes, Andres

Article. 10.3390/cancers12123611. 2020


New Guidelines for optimal patient care with localized colon cancer: recommending what is proven, but also watching what research is bringing.

Tarazona, Noelia; (...); Cervantes, Andres

Editorial Material. 10.1016/j.annonc.2020.07.012. 2020


NRF2 through RPS6 Activation Is Related to Anti-HER2 Drug Resistance in HER2 -Amplified Gastric Cancer.

Gambardella, V; (...); Cervantes, A

Article. 10.1158/1078-0432.CCR-18-2421. 2019


Precision Medicine to Treat Advanced Gastroesophageal Adenocarcinoma: A Work in Progress.

Gambardella, Valentina; (...); Cervantes, Andres

Article. 10.3390/jcm9093049. 2020


Reply to the letter to the editor: adjuvant nivolumab for the management of the pathological residual disease in esophageal or junctional tumors: a word of caution by PK Garg, R. Kumar and P. Dixit

Smyth, E C; (...); Fleitas, T

Letter. 10.1016/j.annonc.2021.05.795. 2021


Targeted next-generation sequencing of circulating-tumor DNA for tracking minimal residual disease in localized colon cancer

Tarazona, N; (...); Cervantes, A

Article. 10.1093/annonc/mdz390. 2019

  • Open Access.

The role of tumor-associated macrophages in gastric cancer development and their potential as a therapeutic target.

Gambardella, V; (...); Fleitas, T

Article. 10.1016/j.ctrv.2020.102015. 2020


Towards precision oncology for anti-HER2 blockade in gastroesophageal adenocarcinoma.

Gambardella, V; (...); Cervantes, A

Review. 10.1093/annonc/mdz143. 2019


Understanding mechanisms of primary resistance to checkpoint inhibitors will lead to precision immunotherapy of advanced gastric cancer

Gambardella, V, Fleitas, T, Cervantes, A

Editorial Material. 10.1093/annonc/mdz008. 2019


Understanding the clinical behavior of relapsed colon cancers with microsatellite instability relative to BRAF mutations.

Roda, D, Rosello, S, Cervantes, A

Editorial Material. 10.1093/annonc/mdz229. 2019


Will Organoids Fill the Gap towards Functional Precision Medicine?

Papaccio, Federica; (...); Cervantes, Andres

Article. 10.3390/jpm12111939. 2022


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