Identificación de nuevos mecanismos implicados en la angiogénesis e inflamación en pacientes obesos. Modulación por ligandos de receptores nucleares constitutivos de androstano.

Datos básicos

PROYECTO DE INVESTIGACIÓN NACIONAL F.COMPETITIVA FIN. PUBLICA 173.333,00 € PI18/00209 HOSPITAL CLINICO UNIVERSITARIO DE VALENCIA Año de incio: 2019 Año de finalización: 2022

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Grupos y Plataformas de I+D+i

Financiadores - Promotores

INSTITUTO SALUD CARLOS III

Resultados del Ensayo Clínico


Activation of the Constitutive Androstane Receptor Inhibits Leukocyte Adhesiveness to Dysfunctional Endothelium.

Lopez-Riera, M; (...); Piqueras, L

Article. 10.3390/ijms22179267. 2021


An updated overview of e-cigarette impact on human health.

Marques, P, Piqueras, L, Sanz, MJ

Article. 10.1186/s12931-021-01737-5. 2021


Angiotensin II and leukocyte trafficking: New insights for an old vascular mediator. Role of redox-signaling pathways.

Piqueras, Laura, Sanz, Maria-Jesus

Article. 10.1016/j.freeradbiomed.2020.02.002. 2020


Anti-inflammatory effects and improved metabolic derangements in ob/ob mice by a newly synthesized prenylated benzopyran with pan-PPAR activity

Marques, Patrice; (...); Cabedo, Nuria

Article. 10.1016/j.phrs.2022.106638. 2023


Association of chemokines IP-10/CXCL10 and I-TAC/CXCL11 with insulin resistance and enhance leukocyte endothelial arrest in obesity.

Moreno, Beatriz; (...); Real, Jose T

Article. 10.1016/j.mvr.2021.104254. 2022


Beneficial effects of PCSK9 inhibition with alirocumab in familial hypercholesterolemia involve modulation of new immune players

Marques, P; (...); Sanz, MJ

Article. 10.1016/j.biopha.2021.112460. 2022

  • Open Access.

Frailty Is Associated with Oxidative Stress in Older Patients with Type 2 Diabetes.

Alabadi, B; (...); Real, JT

Article. 10.3390/nu13113983. 2021


Oral Unsaturated Fat Load Impairs Postprandial Systemic Inflammation in Primary Hypercholesterolemia Patients.

Collado, A; (...); Sanz, MJ

Article. 10.3389/fphar.2021.656244. 2021


Peripheral blood levels of CXCL10 are a useful marker for diabetic polyneuropathy in subjects with type 2 diabetes.

Ascaso, Pilar; (...); Real, Jose T

Article. 10.1111/ijcp.14302. 2021


Role of antiangiogenic VEGF-A165b in angiogenesis and systolic function after reperfused myocardial infarction.

Rios-Navarro, Cesar; (...); Bodi, Vicente

Article. 10.1016/j.rec.2020.03.013. 2021


The radiographic assessment of lung edema score of lung edema severity correlates with inflammatory parameters in patients with coronavirus disease 2019-Potential new admission biomarkers to predict coronavirus disease 2019 worsening.

Marques P; (...); Sanz MJ

Article. 10.3389/fmed.2022.871714. 2022


Therapeutic inertia in patients with type 2 diabetes treated with non-insulin agents.

Ampudia-Blasco, F Javier; (...); Real, Jose T

Article. 10.1016/j.jdiacomp.2020.107828. 2021


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