Portal de investigación
Identificación de nuevos mecanismos implicados en la angiogénesis e inflamación en pacientes obesos. Modulación por ligandos de receptores nucleares constitutivos de androstano.
Datos básicos
- Protocolo:
- PI18/00209
- EUDRACT:
- NCT:
- Centro:
- HOSPITAL CLINICO UNIVERSITARIO DE VALENCIA
- Año de incio:
- 2019
- Año de finalización:
- 2022
Documentos
- No hay documentos
Participantes
Grupos y Plataformas de I+D+i
Financiadores - Promotores
Resultados del Ensayo Clínico
Activation of the Constitutive Androstane Receptor Inhibits Leukocyte Adhesiveness to Dysfunctional Endothelium.
Lopez-Riera, M; (...); Piqueras, L
Article. 10.3390/ijms22179267. 2021
An updated overview of e-cigarette impact on human health.
Marques, P, Piqueras, L, Sanz, MJ
Article. 10.1186/s12931-021-01737-5. 2021
Angiotensin II and leukocyte trafficking: New insights for an old vascular mediator. Role of redox-signaling pathways.
Piqueras, Laura, Sanz, Maria-Jesus
Article. 10.1016/j.freeradbiomed.2020.02.002. 2020
Anti-inflammatory effects and improved metabolic derangements in ob/ob mice by a newly synthesized prenylated benzopyran with pan-PPAR activity
Marques, Patrice; (...); Cabedo, Nuria
Article. 10.1016/j.phrs.2022.106638. 2023
Association of chemokines IP-10/CXCL10 and I-TAC/CXCL11 with insulin resistance and enhance leukocyte endothelial arrest in obesity.
Moreno, Beatriz; (...); Real, Jose T
Article. 10.1016/j.mvr.2021.104254. 2022
Beneficial effects of PCSK9 inhibition with alirocumab in familial hypercholesterolemia involve modulation of new immune players
Article. 10.1016/j.biopha.2021.112460. 2022
Frailty Is Associated with Oxidative Stress in Older Patients with Type 2 Diabetes.
Alabadi, B; (...); Real, JT
Article. 10.3390/nu13113983. 2021
Novel Immune Features of the Systemic Inflammation Associated with Primary Hypercholesterolemia: Changes in Cytokine/Chemokine Profile, Increased Platelet and Leukocyte Activation
Collado, A; (...); Sanz, MJ
Article. 10.3390/jcm8010018. 2019
Oral Unsaturated Fat Load Impairs Postprandial Systemic Inflammation in Primary Hypercholesterolemia Patients.
Collado, A; (...); Sanz, MJ
Article. 10.3389/fphar.2021.656244. 2021
Peripheral blood levels of CXCL10 are a useful marker for diabetic polyneuropathy in subjects with type 2 diabetes.
Ascaso, Pilar; (...); Real, Jose T
Article. 10.1111/ijcp.14302. 2021
Role of antiangiogenic VEGF-A165b in angiogenesis and systolic function after reperfused myocardial infarction.
Rios-Navarro, Cesar; (...); Bodi, Vicente
Article. 10.1016/j.rec.2020.03.013. 2021
SGLT-2 (Sodium-Glucose Cotransporter 2) Inhibition Reduces Ang II (Anciotensin II)-Induced Dissecting Abdominal Aortic Aneurysm in ApoE (Apolipoprotein E) Knockout Mice
Ortega, R; (...); Piqueras, L
Article. 10.1161/ATVBAHA.119.312659. 2019
Systemic Inflammation in Metabolic Syndrome: Increased Platelet and Leukocyte Activation, and Key Role of CX3CL1/CX3CR1 and CCL2/CCR2 Axes in Arterial Platelet-Proinflammatory Monocyte Adhesion.
Marques, Patrice; (...); Sanz, Maria-Jesus
Article. 10.3390/jcm8050708. 2019
The radiographic assessment of lung edema score of lung edema severity correlates with inflammatory parameters in patients with coronavirus disease 2019-Potential new admission biomarkers to predict coronavirus disease 2019 worsening.
Marques P; (...); Sanz MJ
Article. 10.3389/fmed.2022.871714. 2022
Therapeutic inertia in patients with type 2 diabetes treated with non-insulin agents.
Ampudia-Blasco, F Javier; (...); Real, Jose T
Article. 10.1016/j.jdiacomp.2020.107828. 2021
