RETOS 2017. MODULACION FARMACOLOGICA DEL SISTEMA INMUNE COMO DIANA CLAVE EN LA PREVENCION DE LA ENFERMEDAD CARDIOVASCULAR ASOCIADA A DESORDENES METABOLICOS. SINTESIS DE FARMACOS NOVEDOSOS

1-(2 '-Bromobenzyl)-6,7-dihydroxy-N-methyl-tetrahydroisoquinoline and 1,2-Demethyl-nuciferine as Agonists in Human D-2 Dopamine Receptors

Silva, AG; (...); Cabedo, N

Article. 10.1021/acs.jnatprod.9b00921. 2020

A novel pan-PPAR agonist (BP-2) normalizes metabolic and inflammatory parameters in vitro and in ob/ob mice

Sanz, MJ; (...); Cabedo, N

Meeting Abstract. 2023

Activation of the Constitutive Androstane Receptor Inhibits Leukocyte Adhesiveness to Dysfunctional Endothelium.

Lopez-Riera, M; (...); Piqueras, L

Article. 10.3390/ijms22179267. 2021

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An updated overview of e-cigarette impact on human health.

Marques, P, Piqueras, L, Sanz, MJ

Article. 10.1186/s12931-021-01737-5. 2021

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Angiotensin II and leukocyte trafficking: New insights for an old vascular mediator. Role of redox-signaling pathways.

Piqueras, Laura, Sanz, Maria-Jesus

Article. 10.1016/j.freeradbiomed.2020.02.002. 2020

Anti-inflammatory effects and improved metabolic derangements in ob/ob mice by a newly synthesized prenylated benzopyran with pan-PPAR activity

Marques, Patrice; (...); Cabedo, Nuria

Article. 10.1016/j.phrs.2022.106638. 2023

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Association of chemokines IP-10/CXCL10 and I-TAC/CXCL11 with insulin resistance and enhance leukocyte endothelial arrest in obesity.

Moreno, Beatriz; (...); Real, Jose T

Article. 10.1016/j.mvr.2021.104254. 2022

Beneficial effects of PCSK9 inhibition with alirocumab in familial hypercholesterolemia involve modulation of new immune players

Article. 10.1016/j.biopha.2021.112460. 2022

Design, synthesis, biological evaluation and molecular modelling of substituted pyrrolo[2,1-a]isoquinolinone derivatives: discovery of potent inhibitors of AChE and BChE

Parravicini, O; (...); Enriz, RD

Article. 10.1039/d1nj00345c. 2021

Frailty Is Associated with Oxidative Stress in Older Patients with Type 2 Diabetes.

Alabadi, B; (...); Real, JT

Article. 10.3390/nu13113983. 2021

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Novel Immune Features of the Systemic Inflammation Associated with Primary Hypercholesterolemia: Changes in Cytokine/Chemokine Profile, Increased Platelet and Leukocyte Activation

Collado, A; (...); Sanz, MJ

Article. 10.3390/jcm8010018. 2019

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Oral Unsaturated Fat Load Impairs Postprandial Systemic Inflammation in Primary Hypercholesterolemia Patients.

Collado, A; (...); Sanz, MJ

Article. 10.3389/fphar.2021.656244. 2021

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Pharmacological modulation of redox signaling pathways in disease.

Sanz, Maria Jesus, Alcaraz, Maria Jose

Editorial Material. 10.1016/j.freeradbiomed.2020.04.003. 2020

Platelet hyperactivity as a trigger of platelet-leukocyte-endothelium interactions and subsequent cardiovascular complications in early-stage COPD

Marques, P; (...); Sanz, MJ

Meeting Abstract. 2023

Polycerasoidol, a Natural Prenylated Benzopyran with a Dual PPAR alpha/PPAR gamma Agonist Activity and Anti-inflammatory Effect

Bermejo, A; (...); Cortes, D

Article. 10.1021/acs.jnatprod.9b00003. 2019

Revealing 2-dimethylhydrazino-2-alkyl alkynyl sphingosine derivatives as sphingosine kinase 2 inhibitors: Some hints on the structural basis for selective inhibition.

Corro-Moron, Macarena; (...); Diaz, Yolanda

Article. 10.1016/j.bioorg.2022.105668. 2022

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Role of antiangiogenic VEGF-A165b in angiogenesis and systolic function after reperfused myocardial infarction.

Rios-Navarro, Cesar; (...); Bodi, Vicente

Article. 10.1016/j.rec.2020.03.013. 2021

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SGLT-2 (Sodium-Glucose Cotransporter 2) Inhibition Reduces Ang II (Anciotensin II)-Induced Dissecting Abdominal Aortic Aneurysm in ApoE (Apolipoprotein E) Knockout Mice

Ortega, R; (...); Piqueras, L

Article. 10.1161/ATVBAHA.119.312659. 2019

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Synthesis and biological evaluation of sphingosine kinase 2 inhibitors with anti-inflammatory activity

Vettorazzi, M; (...); Enriz, RD

Article. 10.1002/ardp.201800298. 2019

Synthesis and biological studies of "Polycerasoidol" and "trans-d-Tocotrienolic acid" derivatives as PPARa and/or PPAR? agonists.

Vila, Laura; (...); Cortes, Diego

Article. 10.1016/j.bmc.2021.116532. 2022

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Synthesis of benzopyran derivatives as PPAR alpha and/or PPAR gamma activators

Bermejo, A; (...); Cabedo, N

Article. 10.1016/j.bmc.2019.115162. 2019

Systemic Inflammation in Metabolic Syndrome: Increased Platelet and Leukocyte Activation, and Key Role of CX3CL1/CX3CR1 and CCL2/CCR2 Axes in Arterial Platelet-Proinflammatory Monocyte Adhesion.

Marques, Patrice; (...); Sanz, Maria-Jesus

Article. 10.3390/jcm8050708. 2019

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The angiotensin-(1-7)/Mas receptor axis protects from endothelial cell senescence via klotho and Nrf2 activation

Romero A; (...); Peiró C

Article. 10.1111/acel.12913. 2019

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The dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonism inhibits leukocyte adhesiveness to dysfunctional endothelium

Marques, P; (...); Piqueras, L

Meeting Abstract. 2023

The nuclear retinoid-related orphan receptor RORa controls adipose tissue inflammation in patients with morbid obesity and diabetes.

Ortega, Rebeca; (...); Piqueras, Laura

Article. 10.1038/s41366-021-00787-5. 2021

The radiographic assessment of lung edema score of lung edema severity correlates with inflammatory parameters in patients with coronavirus disease 2019-Potential new admission biomarkers to predict coronavirus disease 2019 worsening.

Marques P; (...); Sanz MJ

Article. 10.3389/fmed.2022.871714. 2022

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Therapeutic inertia in patients with type 2 diabetes treated with non-insulin agents.

Ampudia-Blasco, F Javier; (...); Real, Jose T

Article. 10.1016/j.jdiacomp.2020.107828. 2021