Estudio de nuevos mecanismos inflamatorios y angiogénicos asociados a la obesidad grave morbida: papel del eje CXCR3 y los receptores RORs.
Datos básicos
- Protocolo:
- PI15/00082
- EUDRACT:
- NCT:
- Centro:
- Año de incio:
- 2016
- Año de finalización:
- 2018
Documentos
- No hay documentos
Participantes
Grupos y Plataformas de I+D+i
Financiadores - Promotores
Resultados del Ensayo Clínico
Association of chemokines IP-10/CXCL10 and I-TAC/CXCL11 with insulin resistance and enhance leukocyte endothelial arrest in obesity.
Moreno, Beatriz; (...); Real, Jose T
Article. 10.1016/j.mvr.2021.104254. 2022
Frailty Is Associated with Oxidative Stress in Older Patients with Type 2 Diabetes.
Alabadi, B; (...); Real, JT
Article. 10.3390/nu13113983. 2021
Gene expression profile following an oral unsaturated fat load in abdominal obese subjects.
Garcia-Garcia AB; (...); Ascaso JF
Article. 10.1007/s00394-018-1659-4. 2019
LAM study: Effects of lacosamide on behaviour and quality of life in patients with epilepsy
Alfaro, A; (...); Giner, JC
Article. 10.1016/j.nrl.2016.10.007. 2019
Machine Learning Model in Obesity to Predict Weight Loss One Year after Bariatric Surgery: A Pilot Study.
Nadal, E; (...); Real, JT
Article. 10.3390/biomedicines12061175. 2024
Novel Immune Features of the Systemic Inflammation Associated with Primary Hypercholesterolemia: Changes in Cytokine/Chemokine Profile, Increased Platelet and Leukocyte Activation
Collado, A; (...); Sanz, MJ
Article. 10.3390/jcm8010018. 2019
Peripheral blood levels of CXCL10 are a useful marker for diabetic polyneuropathy in subjects with type 2 diabetes.
Ascaso, Pilar; (...); Real, Jose T
Article. 10.1111/ijcp.14302. 2021
Polycerasoidol, a Natural Prenylated Benzopyran with a Dual PPAR alpha/PPAR gamma Agonist Activity and Anti-inflammatory Effect
Bermejo, A; (...); Cortes, D
Article. 10.1021/acs.jnatprod.9b00003. 2019
SGLT-2 (Sodium-Glucose Cotransporter 2) Inhibition Reduces Ang II (Anciotensin II)-Induced Dissecting Abdominal Aortic Aneurysm in ApoE (Apolipoprotein E) Knockout Mice
Ortega, R; (...); Piqueras, L
Article. 10.1161/ATVBAHA.119.312659. 2019
Systemic Inflammation in Metabolic Syndrome: Increased Platelet and Leukocyte Activation, and Key Role of CX3CL1/CX3CR1 and CCL2/CCR2 Axes in Arterial Platelet-Proinflammatory Monocyte Adhesion.
Marques, Patrice; (...); Sanz, Maria-Jesus
Article. 10.3390/jcm8050708. 2019
The nuclear retinoid-related orphan receptor RORa controls adipose tissue inflammation in patients with morbid obesity and diabetes.
Ortega, Rebeca; (...); Piqueras, Laura
Article. 10.1038/s41366-021-00787-5. 2021