Estudio de nuevos mecanismos inflamatorios y angiogénicos asociados a la obesidad grave morbida: papel del eje CXCR3 y los receptores RORs.

Datos básicos

Protocolo:
PI15/00082
EUDRACT:
NCT:
Centro:
Año de incio:
2016
Año de finalización:
2018
PROYECTO DE INVESTIGACIÓN NACIONAL F.COMPETITIVA FIN. PUBLICA 154.578,00 €

Documentos

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Participantes

Grupos y Plataformas de I+D+i

Financiadores - Promotores

INSTITUTO SALUD CARLOS III

Resultados del Ensayo Clínico


Association of chemokines IP-10/CXCL10 and I-TAC/CXCL11 with insulin resistance and enhance leukocyte endothelial arrest in obesity.

Moreno, Beatriz; (...); Real, Jose T

Article. 10.1016/j.mvr.2021.104254. 2022


Frailty Is Associated with Oxidative Stress in Older Patients with Type 2 Diabetes.

Alabadi, B; (...); Real, JT

Article. 10.3390/nu13113983. 2021


Gene expression profile following an oral unsaturated fat load in abdominal obese subjects.

Garcia-Garcia AB; (...); Ascaso JF

Article. 10.1007/s00394-018-1659-4. 2019


LAM study: Effects of lacosamide on behaviour and quality of life in patients with epilepsy

Alfaro, A; (...); Giner, JC

Article. 10.1016/j.nrl.2016.10.007. 2019


Machine Learning Model in Obesity to Predict Weight Loss One Year after Bariatric Surgery: A Pilot Study.

Nadal, E; (...); Real, JT

Article. 10.3390/biomedicines12061175. 2024

  • Open Access.

Novel Immune Features of the Systemic Inflammation Associated with Primary Hypercholesterolemia: Changes in Cytokine/Chemokine Profile, Increased Platelet and Leukocyte Activation

Collado, A; (...); Sanz, MJ

Article. 10.3390/jcm8010018. 2019


Peripheral blood levels of CXCL10 are a useful marker for diabetic polyneuropathy in subjects with type 2 diabetes.

Ascaso, Pilar; (...); Real, Jose T

Article. 10.1111/ijcp.14302. 2021


Polycerasoidol, a Natural Prenylated Benzopyran with a Dual PPAR alpha/PPAR gamma Agonist Activity and Anti-inflammatory Effect

Bermejo, A; (...); Cortes, D

Article. 10.1021/acs.jnatprod.9b00003. 2019


SGLT-2 (Sodium-Glucose Cotransporter 2) Inhibition Reduces Ang II (Anciotensin II)-Induced Dissecting Abdominal Aortic Aneurysm in ApoE (Apolipoprotein E) Knockout Mice

Ortega, R; (...); Piqueras, L

Article. 10.1161/ATVBAHA.119.312659. 2019


Systemic Inflammation in Metabolic Syndrome: Increased Platelet and Leukocyte Activation, and Key Role of CX3CL1/CX3CR1 and CCL2/CCR2 Axes in Arterial Platelet-Proinflammatory Monocyte Adhesion.

Marques, Patrice; (...); Sanz, Maria-Jesus

Article. 10.3390/jcm8050708. 2019


The nuclear retinoid-related orphan receptor RORa controls adipose tissue inflammation in patients with morbid obesity and diabetes.

Ortega, Rebeca; (...); Piqueras, Laura

Article. 10.1038/s41366-021-00787-5. 2021


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