Grupo de Investigación de Deterioro Neurológico

Responsable de la Unidad de Investigación:

Áreas de investigación

Líneas de investigación

  1. Main Line of research: Characterization of neurological and brain alterations in patients with liver disease. Mechanisms: role of changes in inflammation, immune system, microbiota and extracellular vesicles. Diagnostic and therapeutic implications.
  2. Characterization of cognitive, functional and brain alterations in patients with minimal hepatic encephalopathy (MHE)
  3. Research on cognitive and motor alterations in patients with MASLD with mild cognitive impairment
  4. Characterization of immunological, inflammatory, microbiota and neuroinflammatory alterations associated with the onset of mild cognitive impairment in liver cirrhosis and MASLD.
  5. Identify biomarkers for early detection of mild cognitive impairment in liver cirrhosis and MASLD
  6. To assess the effects of rifaximin treatment and new treatments: mechanisms involved
  7. Identification and modelling of molecular and cellular events of the immune response associated to the appearance of MHE