Portal de investigación
Association between N-terminal pro-brain natriuretic peptide and maximal functional capacity in heart failure with preserved ejection fraction: The modifying role of obesity.
Fecha de publicación:
Fecha Ahead of Print:
Autores de INCLIVA
Participantes ajenos a INCLIVA
- Flor, C
- Marín, P
- Bayés-Genís, A
Grupos y Plataformas de I+D+i
Abstract
This study investigates the association between maximal functional capacity (peakVO(2)) and N-terminal pro-brain natriuretic peptide (NT-proBNP) in 133 ambulatory patients with heart failure with preserved ejection fraction (HFpEF), focusing on patients with obesity. Across all participants, NT-proBNP inversely correlated with peakVO(2). However, this association varied based on obesity status. In patients without obesity, there was an inverse relationship between NT-proBNP and peakVO(2), while no significant correlation was observed in patients with obesity. These findings suggest that in stable ambulatory HFpEF, NT-proBNP did not predict peakVO(2) in patients with obesity.
Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.
Datos de la publicación
- ISSN/ISSNe:
- 1871-403X, 1878-0318
- Tipo:
- Article
- Páginas:
- 226-231
- PubMed:
- 38866642
Obesity Research & Clinical Practice Elsevier BV
Documentos
- No hay documentos
Filiaciones
Keywords
- HFpEF; Maximal functional capacity; NT-proBNP; Obesity; PeakVO(2)
Financiación
Proyectos y Estudios Clínicos
Retirada del Tratamiento Betabloqueante en Pacientes con Insuficiencia Cardíaca con Función Sistólica Preservada e Incompetencia Cronotrópica. Efecto sobre la Capacidad Funcional.
Investigador Principal: JULIO NUÑEZ VILLOTA
PI17/01426 . INSTITUTO SALUD CARLOS III . 2018
Cita
Palau P,Núñez G,de la Espriella R,Miñana G,Domínguez E,Lorenzo M,López L,Flor C,Marín P,Bayés A,Sanchis J,Núñez J. Association between N-terminal pro-brain natriuretic peptide and maximal functional capacity in heart failure with preserved ejection fraction: The modifying role of obesity. Obes. Res. Clin. Pract. 2024. 18. (3):p. 226-231. IF:2,300. (3).
Association between N-terminal pro-brain natriuretic peptide and maximal functional capacity in heart failure with preserved ejection fraction: The modifying role of obesity. Palau P, Núñez G, de la Espriella R, Miñana G, Domínguez E, Lorenzo M, López L et al. Obesity Research & Clinical Practice. 2024 junio 12. 18 (3):226-231. DOI:10.1016/j.orcp.2024.05.005. PMID:38866642.
