Portal de investigación
An update on utilising brain natriuretic peptide for risk stratification, monitoring and guiding therapy in heart failure
Autores de INCLIVA
Participantes ajenos a INCLIVA
- Miro, O
- Bayes-Genis, A
Grupos y Plataformas de I+D+i
Abstract
IntroductionHeart failure (HF) is a dominant health problem with an overall poor prognosis. Natriuretic peptides (NPs) are upregulated in HF as a compensatory mechanism. They have been extensively used for diagnosis and risk stratification.Areas coveredThis review addresses the history and physiology of NPs in order to understand their current role in clinical practice. It further provides a detailed and updated narrative review on the utility of those biomarkers for risk stratification, monitoring, and guiding therapy in HF.Expert opinionNPs show excellent predictive ability in heart failure patients, both in acute and chronic settings. Understanding their pathophysiology and their modifications in specific situations is key for an adequate interpretation in specific clinical scenarios in which their prognostic value may be weaker or less well evaluated. To better promote risk stratification in HF, NPs should be integrated with other predictive tools to develop multiparametric risk models. Both inequalities of access to NPs and evidence caveats and limitations will need to be addressed by future research in the coming years.
Datos de la publicación
- ISSN/ISSNe:
- 1473-7159, 1744-8352
- Tipo:
- Review
- Páginas:
- 521-533
- PubMed:
- 37216616
EXPERT REVIEW OF MOLECULAR DIAGNOSTICS Taylor & Francis
Citas Recibidas en Web of Science: 4
Documentos
- No hay documentos
Filiaciones
Keywords
- Heart failure; Prognosis; Natriuretic peptides; biomarkers; Guiding therapy
Financiación
Proyectos y Estudios Clínicos
INCORPORACIÓN DE NUEVAS ÁREAS TEMÁTICAS Y NUEVOS GRUPOS AL CONSORCIO CIBER
Investigador Principal: JUAN SANCHIS FORES
CB16/11/00420 . INSTITUTO SALUD CARLOS III
Cita
Nunez G,Iraola D,Lorenzo M,de la Espriella R,Villar S,Santas E,Minana G,Sanchis J,Carratala A,Miro O,Bayes A,Nunez J. An update on utilising brain natriuretic peptide for risk stratification, monitoring and guiding therapy in heart failure. Expert Rev. Mol. Diagn. 2023. 23(6):p. 521-533. (1).
An update on utilising brain natriuretic peptide for risk stratification, monitoring and guiding therapy in heart failure. Nunez Marin,G, Iraola,D, Lorenzo,M, de la Espriella,R, Villar,S, Santas,E, Minana,G et al. EXPERT REVIEW OF MOLECULAR DIAGNOSTICS. 2023 junio 03. 23 (6):521-533. DOI:10.1080/14737159.2023.2216386. PMID:37216616.
