Portal de investigación
Venous Leg Compression for Tissue Decongestion in Patients With Worsening Congestive Heart Failure.
Fecha de publicación:
Fecha Ahead of Print:
Autores de INCLIVA
Participantes ajenos a INCLIVA
- Civera, J
- Conesa, A
- Martinez, A
- Nunez, E
- Bayes-Genis, A
Grupos y Plataformas de I+D+i
Abstract
AIMS: Venous leg compression (VLC) with elastic bandages has been proposed as a potentially useful strategy for decreasing tissue congestion. We aimed to evaluate the effect of VLC on short-term changes on intravascular refill, assessed by inferior vena cava (IVC) diameter in patients with worsening heart failure (WHF) requiring parenteral furosemide. Additionally, we sought to evaluate whether early changes in IVC were related to short-term decongestion. METHODS: This is a prospective study in which we included 20 consecutive ambulatory patients with WHF treated with subcutaneous furosemide and VLC for at least 72 h. The endpoints were (a) short-term changes in IVC, (b) the association between decongestion and 3-h IVC changes following VLC. Changes in continuous endpoints and their longitudinal trajectories were estimated with linear mixed regression models. All analyses were adjusted for multiple comparisons. RESULTS: Following administration of subcutaneous furosemide and VLC, we found a significant increase in 3-h IVC diameter ( IVC = 1.6 mm, CI 95%: 0.7-2.5; p < 0.001), with a greater increase in those with baseline IVC=21 mm (2.4 vs. 0.8 mm; p < 0.001). 3-h intravascular refill (increase in IVC=2 mm) was associated with greater decongestion (natriuresis, weight, peripheral edemas, and dyspnea) in those with baseline IVC=21 mm but not when IVC>21 mm (p < 0.05 for all comparisons). CONCLUSIONS: In this cohort of patients with congestive WHF treated with subcutaneous furosemide and VLC, we found a greater increase in short-term IVC in those with IVC =21 mm at baseline. In this subset of patients, a 3-h increase in IVC=2 mm was associated with greater short-term decongestion.
Copyright © 2022 Civera, Miñana, de la Espriella, Santas, Sastre, Mollar, Conesa, Martínez, Núñez, Bayés-Genís and Núñez.
Datos de la publicación
- ISSN/ISSNe:
- 2297-055X, 2297-055X
- Tipo:
- Article
- Páginas:
- 847450-847450
- PubMed:
- 35872894
Frontiers In Cardiovascular Medicine FRONTIERS MEDIA SA
Citas Recibidas en Web of Science: 3
Documentos
Filiaciones
Keywords
- congestion; diuretic efficiency; inferior vena cava; venous leg compression; worsening heart failure
Financiación
Proyectos y Estudios Clínicos
INCORPORACIÓN DE NUEVAS ÁREAS TEMÁTICAS Y NUEVOS GRUPOS AL CONSORCIO CIBER
Investigador Principal: JUAN SANCHIS FORES
CB16/11/00420 . INSTITUTO SALUD CARLOS III
Cita
Civera J,Minana G,de la Espriella R,Santas E,Sastre C,Mollar A,Conesa A,Martinez A,Nunez E,Bayes A,Nunez J. Venous Leg Compression for Tissue Decongestion in Patients With Worsening Congestive Heart Failure. Front. Cardiovasc. Med. 2022. 9. p. 847450-847450. IF:3,600. (2).
Venous Leg Compression for Tissue Decongestion in Patients With Worsening Congestive Heart Failure. Civera J, Minana G, de la Espriella R, Santas E, Sastre C, Mollar A, Conesa A et al. Frontiers In Cardiovascular Medicine. 2022 julio 08. 9847450-847450. DOI:10.3389/fcvm.2022.847450. PMID:35872894.
