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  3. Predictive Value of Cardiac Magnetic Resonance Feature Tracking after Acute Myocardial Infarction: A Comparison with Dobutamine Stress Echocardiography.

Predictive Value of Cardiac Magnetic Resonance Feature Tracking after Acute Myocardial Infarction: A Comparison with Dobutamine Stress Echocardiography.

Fecha de publicación: Fecha Ahead of Print:

Autores de INCLIVA

Participantes ajenos a INCLIVA

  • Valente, FX
  • Gavara, J
  • Gutierrez, L
  • Rello, P
  • Maymi, M
  • Fernandez-Galera, R
  • Monmeneu, JV
  • Sao-Aviles, A
  • Lopez-Lereu, MP
  • Gonzalez-Alujas, MT
  • Moratal, D
  • Cuellar, H
  • Barrabes, J
  • Otaegui, I
  • Evangelista, A
  • Ferreira, I
  • Rodriguez-Palomares, J

Grupos y Plataformas de I+D+i

Abstract

In acute ST-segment elevation myocardial infarction (STEMI) late gadolinium enhancement (LGE) may underestimate segmental functional recovery. We evaluated the predictive value of cardiac magnetic resonance (CMR) feature-tracking (FT) for functional recovery and whether it incremented the value of LGE compared to low-dose dobutamine stress echocardiography (LDDSE) and speckle-tracking echocardiography (STE). Eighty patients underwent LDDSE and CMR within 5-7 days after STEMI and segmental functional recovery was defined as improvement in wall-motion at 6-months CMR. Optimal conventional and FT parameters were analyzed and then also applied to an external validation cohort of 222 STEMI patients. Circumferential strain (CS) was the strongest CMR-FT predictor and addition to LGE increased the overall accuracy to 74% and was especially relevant in segments with 50-74% LGE (AUC 0.60 vs. 0.75, p = 0.001). LDDSE increased the overall accuracy to 71%, and in the 50-74% LGE subgroup improved the AUC from 0.60 to 0.69 (p = 0.039). LGE + CS showed similar value as LGE + LDDSE. In the validation cohort, CS was also the strongest CMR-FT predictor of recovery and addition of CS to LGE improved overall accuracy to 73% although this difference was not significant (AUC 0.69, p = 0.44). Conclusion: CS is the strongest CMR-FT predictor of segmental functional recovery after STEMI. Its incremental value to LGE is comparable to that of LDDSE whilst avoiding an inotropic stress agent. CS is especially relevant in segments with 50-74% LGE where accuracy is lower and further testing is frequently required to clarify the potential for recovery.

Datos de la publicación

ISSN/ISSNe:
2077-0383, 2077-0383

Journal of Clinical Medicine  MDPI

Tipo:
Article
Páginas:
-
PubMed:
34830543

Citas Recibidas en Web of Science: 3

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Keywords

  • acute ST-segment elevation myocardial infarction; cardiac magnetic resonance feature-tracking; low-dose dobutamine stress echocardiography; myocardial deformation; speckle-tracking echocardiography

Campos de Estudio

Financiación

INSTITUTO SALUD CARLOS III (CB16/11/00486)

Proyectos y Estudios Clínicos

INCORPORACIÓN DE NUEVAS ÁREAS TEMÁTICAS Y NUEVOS GRUPOS AL CONSORCIO CIBER

Investigador Principal: VICENT BODÍ PERIS

CB16/11/00486 . INSTITUTO SALUD CARLOS III

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