Portal de investigación
Desarrollo quimico y farmacologico de nuevos farmacos "multidiana" en el tratamiento de la diabetes mellitus tipo 2 y la enfermedad cardiovascular asociada
Datos básicos
Documentos
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Participantes
Grupos y Plataformas de I+D+i
Financiadores - Promotores
INSTITUTO SALUD CARLOS III
Resultados del Ensayo Clínico
1-(2 '-Bromobenzyl)-6,7-dihydroxy-N-methyl-tetrahydroisoquinoline and 1,2-Demethyl-nuciferine as Agonists in Human D-2 Dopamine Receptors
Silva, AG; (...); Cabedo, N
Article. 10.1021/acs.jnatprod.9b00921. 2020
Anti-inflammatory effects and improved metabolic derangements in ob/ob mice by a newly synthesized prenylated benzopyran with pan-PPAR activity
Marques, Patrice; (...); Cabedo, Nuria
Article. 10.1016/j.phrs.2022.106638. 2023
Benzopyran hydrazones with dual PPARa/? or PPARa/d agonism and an anti-inflammatory effect on human THP-1 macrophages
García, A; (...); Cortes, D
Article. 10.1016/j.ejmech.2024.116125. 2024
Design, synthesis, biological evaluation and molecular modelling of substituted pyrrolo[2,1-a]isoquinolinone derivatives: discovery of potent inhibitors of AChE and BChE
Parravicini, O; (...); Enriz, RD
Article. 10.1039/d1nj00345c. 2021
Natural products and analogs as preventive agents for metabolic syndrome via peroxisome proliferator-activated receptors: An overview.
Villarroel-Vicente, Carlos; (...); Cabedo, Nuria
Article. 10.1016/j.ejmech.2021.113535. 2021
Synthesis and biological studies of "Polycerasoidol" and "trans-d-Tocotrienolic acid" derivatives as PPARa and/or PPAR? agonists.
Vila, Laura; (...); Cortes, Diego
Article. 10.1016/j.bmc.2021.116532. 2022
Synthesis of 2-Prenylated Alkoxylated Benzopyrans by Horner-Wadsworth-Emmons Olefination with PPARa/? Agonist Activity.
Garcia, A; (...); Cortes, D
Article. 10.1021/acsmedchemlett.1c00400. 2021
