Managing Frailty. A comprehensive approach to promote a disability-free advanced age in Europe: the ADVANTAGE initiative

Datos básicos

Protocolo:
724099
EUDRACT:
NCT:
Centro:
Año de incio:
2016
Año de finalización:
2019
PROYECTO DE INVESTIGACIÓN EUROPEA F.COMPETITIVA FIN. PUBLICA 130.005,00 €

Documentos

  • No hay documentos

Participantes

Grupos y Plataformas de I+D+i

Financiadores - Promotores

EUROPEAN COMMISSION

Resultados del Ensayo Clínico


BCL-xL, a Mitochondrial Protein Involved in Successful Aging: From C. elegans to Human Centenarians

Borras, C; (...); Vina, J

Review. 10.3390/ijms21020418. 2020


Centenarians overexpress pluripotency-related genes.

Inglés M; (...); Viña J

Article. 10.1093/gerona/gly168. 2019


Centenarians: An excellent example of resilience for successful ageing

Borras, C; (...); Vina, J

Review. 10.1016/j.mad.2019.111199. 2020


Early reductive stress and late onset overexpression of antioxidant enzymes in experimental myocardial infarction

Carretero, A; (...); Vina, J

Article. 10.1080/10715762.2020.1735632. 2020


Extracellular vesicles and redox modulation in aging.

Borras, Consuelo; (...); Vina, Jose

Review. 10.1016/j.freeradbiomed.2019.11.032. 2020


Extracellular Vesicles from Healthy Cells Improves Cell Function and Stemness in Premature Senescent Stem Cells by miR-302b and HIF-1alpha Activation.

Mas-Bargues, Cristina; (...); Borras, Consuelo

Article. 10.3390/biom10060957. 2020


Long-term exercise training improves memory in middle-aged men and modulates peripheral levels of BDNF and Cathepsin B

De la Rosa, A; (...); Gomez-Cabrera, MC

Article. 10.1038/s41598-019-40040-8. 2019


Methionine transsulfuration pathway is upregulated in long-lived humans.

Mota-Martorell, Natalia; (...); Reinald, Pamplona

Article. 10.1016/j.freeradbiomed.2020.11.026. 2020


Modulating Oxidant Levels to Promote Healthy Aging

Vina, J; (...); Gomez-Cabrera, MC

Article. 10.1089/ars.2020.8036. 2020


Physical exercise in the prevention and treatment of Alzheimer's disease.

De la Rosa, Adrian; (...); Gomez-Cabrera, Mari Carmen

Article. 10.1016/j.jshs.2020.01.004. 2020


Redox lipidomics to better understand brain aging and function.

Pamplona R; (...); Viña J

Review. 10.1016/j.freeradbiomed.2019.03.016. 2019


Redox modulation of muscle mass and function.

Gomez-Cabrera, M C; (...); Vina, J

Article. 10.1016/j.redox.2020.101531. 2020


Relation Between Genetic Factors and Frailty in Older Adults.

Ingles, Marta; (...); Vina, Jose

Article. 10.1016/j.jamda.2019.03.011. 2019


Relationship between Diet, Microbiota, and Healthy Aging.

Sanchez-Morate, Elisa; (...); Mas-Bargues, Cristina

Article. 10.3390/biomedicines8080287. 2020


Relevance of Oxygen Concentration in Stem Cell Culture for Regenerative Medicine

Mas-Bargues, C; (...); Borras, C

Review. 10.3390/ijms20051195. 2019


Resveratrol shifts energy metabolism to increase lipid oxidation in healthy old mice

Gimeno-Mallench, L; (...); Vina, J

Article. 10.1016/j.biopha.2019.109130. 2019


Sarcopenia, frailty and their prevention by exercise.

Nascimento CM; (...); Viña J

Review. 10.1016/j.freeradbiomed.2018.08.035. 2019


Sex Differences in Age-Associated Type 2 Diabetes in Rats-Role of Estrogens and Oxidative Stress

Diaz, A; (...); Borras, C

Article. 10.1155/2019/6734836. 2019


The free radical theory of frailty: Mechanisms and opportunities for interventions to promote successful aging.

Viña J

Article. 10.1016/j.freeradbiomed.2019.01.045. 2019


Campos de Estudio

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