1. Inicio
  2. Grupos y Plataformas de I+D+i
  3. Grupo de Investigación en Ejercicio, Nutrición y Estilo de Vida Saludable
  4. Áreas y líneas de investigación

Grupo de Investigación en Ejercicio, Nutrición y Estilo de Vida Saludable

Responsable de la Unidad de Investigación:

Maria Carmen Gomez Cabrera

Established Researcher

Áreas de investigación

Líneas de investigación

  1. Mitochondrial Therapeutics in Aging • Investigate the role of nicotinamide riboside (NR), piceid and harmol as a mitotherapeutic agent to reverse age-associated energy collapse and improve mitochondrial function in skeletal muscle. • Explore how glucose-6-phosphate dehydrogenase (G6PD) activation influences redox balance and energy metabolism, and assess its potential in preventing or reversing frailty.
  2. Multimodal Lifestyle Interventions in Aging and Frailty • Develop and evaluate integrated interventions combining multicomponent physical exercise programs with nutritional supplementation to reverse or prevent frailty. • Assess the impact of high-intensity interval training (HIIT) on physical function, muscle health in aging populations. • Study the effects of glucosamine supplementation on physical performance and musculoskeletal integrity in older adults.
  3. Muscle Regeneration and Sarcopenia • Develop strategies to enhance the intrinsic myofiber self-repair mechanisms and regenerative capacity to prevent sarcopenia and muscle wasting in frail individuals. • Elucidate the molecular pathways involved in muscle atrophy, focusing on the contribution of oxidative stress and disuse in clinical and preclinical models.
  4. Exercise Biology and Redox Regulation in Skeletal Muscle • Characterize cell signaling pathways activated during different modalities of physical exercise in skeletal muscle. • Analyze the role of oxidative stress and antioxidant supplementation in modulating exercise responses and protecting against muscle damage.
  5. Translational Research and Clinical Application • Use molecular and cellular approaches in both animal and human models to define the biological mechanisms modulated by exercise and nutrition. • Design clinical trials to translate basic research findings into interventions that enhance quality of life and promote healthy aging.