Áreas de investigación
Líneas de investigación
- Experimental studies on the protective effect against arrhythmic vulnerability. Modifications of the signaling pathways involved in mechanoelectric coupling and activated in situations of mechanical stretch and metabolic overload.
- New therapeutic targets related to: a) calcium homeostasis; b) renin angiotensin aldosterone system/neprilysin inhibition; c) common nodes in the signaling pathways (CaMKII) and d) transmembrane ionic currents.
- Study of the mechanisms involved in the deterioration of the systolic function, fibrosis and the inducibility of arrhythmias in an experimental model of myocardial infarction.
- Study of electrophysiological modifications and inducibility of cardiac arrhythmias in an experimental model of metabolic syndrome
- Development and extension of technical tools for the recording, processing and analysis of cardiac electrophysiological signals based on multielectrodes and cardiac mapping systems