Grupo de investigación en envejecimiento y ejercicio físico

Responsable de la Unidad de Investigación:

Áreas de investigación

Aging: identification of genes associated with aging, particularly genes that are specific in centenary people. Implication of the estrogens and phytoestrogens in the prevention of age-related damage. Research about the involvement of the aryl hydrocarbon receptor (AhR) signaling pathway in the aging process.
Physical activity: identification of the molecular mechanisms by which physical activity is good for health. Identification of the mechanisms by which physical activity and antioxidant supplements help preventing primary and secondary sarcopenia in both human and animal studies. Identification of the best exercise intervention to delay and to treat frailty in humans
Physiopathology of the Alzheimer's disease: identification of the mechanisms by which free radicals, originators of the oxidative stress are used to unleash cell signals that lead to cell death in Alzheimer disease
Study of the modulation of the AhR pathway through the identification of endogenous and exogenous ligands, including nutritional supplements and microbiota-derived metabolites, aimed at improving and treating pathological conditions. This includes evaluating its impact on diseases and age-related physiological decline.